Method for testing toxicity of chemical substance by using nemat

Chemistry: analytical and immunological testing – Process or composition for determination of physical state...

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424 9, 435 29, 435172, 436183, G01N 3348

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active

044448910

ABSTRACT:
Disclosed is a toxicity test for chemical substances using the phylum Nematoda.
According to this test, substances can be easily, rapidly, and inexpensively analyzed for their ability to induce mutations, promote tumor formation, act as teratogens, and cause abnormalities in development, metabolic function, and neuromuscular function.

REFERENCES:
patent: 4066510 (1978-01-01), Thilly
patent: 4129643 (1978-12-01), Clayton
Epstein et al., Chem. Abstr., vol. 82, 1975, No. 167804v.
Edgar et al., Science 198(4323) 1285-1286, Dec. 23, 1977.
Dusenbery, Chem. Abstr., vol. 81, No. 87533v.
Epstein et al., J. Mol. Biol. (1974) 90, 291-300.

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