Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-10-27
1999-09-07
Campbell, Eggerton A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 917, C12Q 168, C12P 1934
Patent
active
059486236
ABSTRACT:
The present invention relates to a novel method for testing the developmental status in pancreatic cells of a mammal. The present invention further relates to applications in the medical field that directly arise from the method of the invention. Additionally, the present invention relates to transgenic mammals comprising at least one inactivated Pax4 allele and optionally at least one inactivated Pax6 allele.
REFERENCES:
Griffin C., Cancer Research 55, pp. 2394-2399, Jun. 1, 1995.
Achille A., et al., Cancer Research 56, pp. 3808-3813, Aug. 15, 1996.
Maulbecker and Gruss, The Embo Journal, vol. 12, No. 6, pp. 2361, 2367, 1. 3
Dressler and Douglass, Proc. Natl. Acad. Sci., USA, vol. 89, pp. 1179-1183, Feb. 1992.
Barr et al., Nature Genetics, vol. 3, pp. 113-117, Feb. 1993.
Stapleton et al., Nature Genetics, vol. 3, pp. 292-298, Apr. 1993.
Glaser et al., Science, vol. 250, pp. 823-827, Nov. 9, 1990.
Hanson et al., Nature Genetics, vol. 6, pp. 168-173, Feb. 1994.
Donehower, Seminars in Cancer Biology, vol. 7, pp. 269-278, 1996.
Perl et al., Nature, vol. 392, pp. 190-193, Mar. 12, 1998.
Parangi et al., Proc. Natl. Acad. Sci., vol 93, pp. 2002-2007, Mar. 1996.
Christofori et al., Nature Genetics, vol. 10, pp. 196-201, Jun. 1995.
Calhoun et al., Nature, vol. 395, pp. 755-756, Oct. 22, 1998.
Sturchler-Pierrat et al., Proc. Natl. Acad. Sci., vol. 94, pp. 13287-13292, Nov. 1997.
Gruss Peter
Sosa-Pineda Beatriz
Campbell Eggerton A.
Kowalski Thomas J.
Max-Planck -Gesellschaft zur Forderung der Wissenschaften e.V.
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