Chemistry: analytical and immunological testing – Rate of reaction determination
Reexamination Certificate
2005-03-08
2005-03-08
Gakh, Yelena G. (Department: 1743)
Chemistry: analytical and immunological testing
Rate of reaction determination
C326S131000, C326S131000, C326S085000
Reexamination Certificate
active
06864090
ABSTRACT:
The present invention provides a novel method for monitoring the reaction kinetics of the biodegradable polymers, and the surface concentration of a drug in a polymer blend matrix. Detailed information on surface concentration, degradation rates, degradation kinetics and mechanism, is provided by using Time-of-Flight Secondary Ion Mass Spectrometry (ToF SIMS) measurements. Also provided is a method for determining oligomers in hydrolyzed biodegradable polymers.
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Chen Jiaxing
Gardella, Jr. Joseph A.
Hernandez de Gatica Norma L.
Lee Joo-Woon
Gakh Yelena G.
Hodgson & Russ LLP
Research Foundation of State University of New York at Buffalo
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