Method for testing infectious disease causing microorganisms

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

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435 39, 435 40, C12Q 104

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active

058769595

ABSTRACT:
A method for detecting, identifying and measuring infectious disease causing microorganisms is described. The method utilizes a plural medium arrangement in which a test liquid containing a microorganism is simultaneously introduced. Different media are utilized for the plural medium arrangement and at least one of the media can contain a respiration inhibiting material and/or other reagents such as antibiotics. Dissolved oxygen measurements of the media are taken as a measurement of microorganism respiration. Oxygen electrode signals within different media are compared and differential respiration variation rates are determined and identification signals produced. The identification signal resulting from the multiple respiration rate determinations is compared with known values to identify and measure the microorganism. The drug sensitivity of a microorganism is also judged when at least one of the media contains a drug for which the sensitivity of microorganism is to be determined.

REFERENCES:
patent: 3957583 (1976-05-01), Gibson
patent: 4220715 (1980-09-01), Ahnell
patent: 4246343 (1981-01-01), Wilkins et al.
patent: 4288543 (1981-09-01), Sielaff et al.
patent: 4311794 (1982-01-01), Melnick et al.
patent: 4321322 (1982-03-01), Ahnell
patent: 4350763 (1982-09-01), Suzuki
patent: 4861709 (1989-08-01), Ulitzur et al.
patent: 5160604 (1992-11-01), Nakamura
WPI/Derwent Abstract 89-303650, Figures 1-7, corresponds to JP-A-01222767 listed above.

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