Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Statutory Invention Registration
2008-05-06
2008-05-06
Carone, Michael J. (Department: 3641)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
C702S023000
Statutory Invention Registration
active
10779192
ABSTRACT:
For use in estimating or predicting bioaccumulation of a chemical analyte, even a surfactant, log Powvalues for the analyte may be determined by calculating the log of the ratio of the concentrations of the analyte in n-octanol and in water, equilibrated using a slow-stir method. In this method, samples of the analyte are prepared and stirred in n-octanol and water (or other largely immiscible solvents) at a rate sufficiently low to avoid emulsions over time at a constant temperature. After stirring, the n-octanol layer and the water layer are sampled and the quantity of analyte in each measured.
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OECD Guideline for the Testing of Chemicals No. 107, entitled “Partition Coefficient (n-octanol/water): Shake Flask Method,” adopted Jul. 27, 1995 by the Council for the Organisation for Economic Co-Operation and Development, Paris, France.
OECD Guideline for the Testing of Chemicals No. 117, entitled “Partition Coefficient (n-octanol/water), High Performance Liquid Chromatography (HPLC) Method,” adopted Mar. 30, 1989 by the Council for the Organisation for Economic Co-Operation and Devolopment, Paris, France.
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Karcher Arron L.
Wilson J. Michael
Carone Michael J.
Halliburton Energy Service,s Inc.
Roddy Craig W.
Tripp Karen B.
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