Method for targeting lysosomal enzymes

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S128000, C514S007600, C514S008500, C424S185100, C536S023100, C435S069100, C435S069700, C435S070100, C435S183000

Reexamination Certificate

active

07858576

ABSTRACT:
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.

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