Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1988-03-09
1990-02-06
Robinson, Ellis P.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424469, 424470, A61K 920
Patent
active
048987360
ABSTRACT:
Dose uniformity in formulations of highly potent drugs may be achieved by distributing a solution of the active ingredient over a directly compressible tableting vehicle with subsequent evaporation of the solvent, followed by tableting.
REFERENCES:
patent: 4489026 (1984-12-01), Yalkowsky
patent: 4710504 (1987-12-01), Baldwin et al.
patent: 4719228 (1988-01-01), Rawlins
Cox, J. Pharm. Pharmaco 1968, 20(3), 238-239.
DiPrima Joseph F.
Howe Leon R.
Merck & Co. , Inc.
Nicholson William H.
Robinson Ellis P.
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