Method for synthesizing sevoflurane and an intermediate thereof

Details Method for synthesizing sevoflurane and an intermediate thereof Method for synthesizing sevoflurane and an intermediate thereof

1999-03-26

2000-08-08

Carr, Deborah D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568681, 568682, 568684, C07C 4109, C07C 4122

Patent

active

061004340

ABSTRACT:
A method for synthesizing fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether. The method includes the step of combining in the presence of aluminum trichloride a quantity of hexafluoroisopropanol and a quantity of either 1,3,5-trioxane or paraformaldehyde to produce sevochlorane. The resulting sevochlorane is then combined with an alkali metal fluoride to produce fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether.

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patent: 5886239 (1999-03-01), Kudzma et al.

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