Method for synthesizing pyrazolobenzodiazepines

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

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Reexamination Certificate

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06916923

ABSTRACT:
Disclosed is a novel method for synthesizing pyrazolobenzodiazepines of formula Iusing intermediates of formulaPyrazolobenzodiazepines of formula I are useful in the treatment and control of solid tumors.

REFERENCES:
patent: 0 988 863 (2000-03-01), None
patent: WO 98/14450 (1998-04-01), None
Berghot, M. A., Arch. Pharm. 325: 285-289 (1992).
Chemical Abstracts, vol. 117, no. 7, Aug. 17, 1992.
Zaharevitz, D. W. et al. Cancer Research, US, American Association for Cancer Research, Baltimore, MD vol. 59, no. 59, Jun. 1, 1999, pp. 2566-2569, XP002118393.

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