Method for synthesizing bisphosphonate

Details Method for synthesizing bisphosphonate Method for synthesizing bisphosphonate

2007-05-08

2007-05-08

O'Sullivan, Peter (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus acids or salts thereof

Reexamination Certificate

active

11252668

ABSTRACT:
The invention relates to a novel multi step synthesis of 3-(N-methyl-N-pentyl) amino-1-hydroxypropane-1,1-diphosphonic acid, monosodium salt, monohydrate, of the formula

REFERENCES:
patent: 3919321 (1975-11-01), Kyburz et al.
patent: 4220611 (1980-09-01), Wolf
patent: 4876339 (1989-10-01), Blum et al.
patent: 4927814 (1990-05-01), Gall et al.
patent: 4942157 (1990-07-01), Gall et al.
patent: 5002937 (1991-03-01), Bosies et al.
patent: 252 504 (1988-01-01), None
patent: 332 068 (1989-09-01), None
patent: 350 002 (1990-01-01), None
patent: 402 152 (1990-12-01), None
patent: WO 01/57052 (2001-09-01), None
patent: WO 03/097655 (2003-11-01), None
Widler, L., et al., Journal of Medicinal Chemistry, vol. 45, No. 17, pp. 3721-3738 (2002).
Hale, W. J., et al., Journal of the American Chemical Society, vol. 42, No. 1, pp. 107-116 (1920).
Galin, F.Z., et al., Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science, vol. 37, No. 4, pp. 708-712 (1988).
Freifelder, M., et al., Journal of the American Chemical Society, vol. 80, No. 16, pp. 4320-4323 (1958).

Affiliated with

Also associated with

Rating

Method for synthesizing bisphosphonate does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for synthesizing bisphosphonate, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for synthesizing bisphosphonate will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3751191