Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-12-27
2005-12-27
Riley, Jezia (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023100, C536S025300
Reexamination Certificate
active
06979540
ABSTRACT:
This invention concerns the use, for synthesizing and immobilising nucleic acids, of a solid support modified by an organized self-assembled monolayer of one or several organosilicon compounds. The invention also concerns methods for synthesizing and immobilizing nucleic acids on such a silanized solid support, and DNA chips obtained by said methods.
REFERENCES:
Maskos et al Nucleic Acids Research, 1992, vol. 20, No. 7 pp. 1679-1684.
Lee et al. Langmuir, 1993, 9, pp. 3009-3014.
International PCT Patent Application No. PCT/FR01/00139, filed Jan. 17, 2001, International Publication No. WO 01/00139, published Jul. 26, 2001.
PCT International Search Report Jul. 5, 2001.
English translation of International PCT Patent Application No. PCT/FR01/00139, filed PCT/FR01/00139, filed Jan. 17, 2001, International Publication No. WO 01/00139, published Jul. 26, 2001.
Publication: “Covalent Attachment Of Synthetic DNA To Self-Assembled Monolayer Films”, by Linda A Chrisey, Gil U Lee and C. Elizabeth O'Ferral, of Naval Research Laboratory Washington, DC, published by Nucleic Acids Research, 1996, vol. 24, No. 15, pp. 3031-3039, XP-002149193.
Publication: “Functionalized Siloxy-Anchored Monolayers With Exposed Amino, Azido, Bromo, or Cyano Groups”, by Natarajan Balachanader and Chaim N. Sukenik of Chemistry Department, Case Western Reserve University, Cleveland, OH, presented at Tetrahedron Letters, vol. 29, No. 44, pp. 5593-5594, 1988, printed in Great Britain, XP-002149194.
Publication: “Fabrication Of Patterned DNA Surfaces”, by Linda A Chrisey, C. Elizabeth O'Ferral, Barry J. Spargo, Charles S. Dulcey and Jeffrey M. Calvert of Naval research Laboratory Washington, DC, published by Nucleic Acids Research, 1996, vol. 24, No. 15, pp. 3040-3047, XP002913337.
Publication: “Synthesis Of Model Compounds For the Formation Of Self-Assembled Monolayers On A Silicon Surface”, by Franz Effenberger and Stephan Heid of Institut for Organische Chemie Der Universitate, Stuttgart, Germany, Sep. 1995, pp. 1126-1130, XP-002149195.
Benneteau Bernard
Bousbaa Jamal
Choplin Franck
Cloarec Jean-Pierre
Martin Jean-Rene
Centre National da la Recherche Scientifique
Riley Jezia
Tolpin Thomas W.
Welsh & Katz Ltd.
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