Method for synthesis of penicillin

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07D49912

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042514428

ABSTRACT:
This invention relates to a method for synthesizing a penicillin by reacting a silylate of 6-aminopenicillanic acid and a carboxylic acid halide in the presence of an insoluble weakly basic resin having a three-dimensional structure.

REFERENCES:
patent: 3478018 (1969-11-01), Robinson et al.
patent: 3479338 (1969-11-01), Adams
patent: 3595855 (1971-07-01), Robinson
patent: 3654266 (1972-04-01), Robinson
patent: 3678037 (1972-07-01), Robinson
patent: 3980637 (1976-09-01), Grossman et al.

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