Method for synthesis of...

Details Method for synthesis of... Method for synthesis of...

2011-03-08

2011-03-08

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S312000

Reexamination Certificate

active

07902365

ABSTRACT:
The present invention provides process for synthesis of 8-methoxy-9H-isothiazolo[5,4-b]quinoline-3,4-diones and 8A,9-dihydro-4aH-isothiazolo[5,4-b]quinoline-3,4-diones of the Formula A.The substituents R, R5, R6, R7, R8and R9are defined herein. The invention also provides novel synthetic intermediates useful in the synthesis of 8-methoxy-9H-isothiazolo[5,4-b]quinoline-3,4-diones and 8A,9-dihydro-4aH-isothiazolo[5,4-b]quinoline-3,4-diones.

REFERENCES:
patent: 7456288 (2008-11-01), Rao et al.
patent: 2005019228 (2005-03-01), None
patent: 2006118605 (2006-11-01), None
patent: 2007014308 (2007-01-01), None
Hashimoto, et al., “Practical Synthesis and Molecular Structure of a Potent Broad-Spectrum Antibacterial Isothiazoloquinolone,” Organic Process Research & Development, 11: 389-398(2007).
International Search Report for Patent Application No. PCT/US2007/018251 dated Jan. 2, 2008.
Wang, et al., “Isothiazoloquinolones with Enhanced Antistaphylococcal Activiites against Multidrug-Resistant Strains: Effects of Structural Modifications at the 6-, 7-, and 8- Positions, ” J. Med. Chem., 50: 199-201 (2007).

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