Method for sustained and extended corneal analgesia

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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514912, A61K 3124

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active

056101848

ABSTRACT:
A method for sustained and extended corneal analgesia by repeated administration of ophthalmic analgesic solutions or preparations containing ultralow nontoxic subanesthetic concentrations of local anesthetic agents. A method for corneal analgesia has a fast onset of pain relief and extended duration of the corneal analgesia for several months without accompanying toxic symptoms by administering to a patient an ophthalmic analgesic solution containing a local anesthetic agent in ultralow concentration between about 0.001% and about 0.05%.

REFERENCES:
patent: 5411738 (1995-05-01), Hind
Paul M. H. Cherry, et al., The Treatment of Pain Following Photorefractive Keratectomy, Supplement to Journal of Refractive and Corneal Surgery, vol. 10, pp. 222-225, Mar./Apr. 1994.
Verna S., et al., Pain Control After PRK: Do Topical Anesthetics Have a Role?, American Academy of Ophthalmology, Annual Meeting, p. 102, Nov. 1995.

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