Coating processes – Particles – flakes – or granules coated or encapsulated – Resin base
Reexamination Certificate
2007-10-16
2007-10-16
Sellers, Robert (Department: 1712)
Coating processes
Particles, flakes, or granules coated or encapsulated
Resin base
C427S220000, C428S407000, C525S328800, C525S332200, C525S385000
Reexamination Certificate
active
11224550
ABSTRACT:
A method for hydrophilization and/or surface area enlargement of a porous base matrix comprising on its inner and/or outer surfaces a polymer (P′) carrying nucleophilic groups X′. The method is characterized in(a) ethoxylating a plurality of said X′ thereby transforming them to groups comprising —(CH2CH2O)nH, or(b) (i) ethoxylating a polymer (P″) carrying nucleophilic groups X″ thereby transforming P″ to a polyhydroxy polymer (P′″) carrying a plurality of —(CH2CH2O)nH groups, whereafter(ii) P′″ is attached to the base matrix.n is an integer ≧1.A support matrix which is obtainable by the method. The support matrix has a sufficient rigidity and swellability to permit liquid flow of a velocity >5 cm/h through the matrix when in form of particles packed to a bed or in form of a porous monolithic plug.The use of the support matrix defined in liquid chromatography, cell culturing, stepwise solid phase synthesis of organic molecules, affinity adsorption in suspensions, solid phase catalysis with an immobilized catalyst.
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Derand Helene
Nasman, legal representative Harry
Nasman, legal representative Rose
GE Healthcare Bio-Sciences AB
Ji Yongggang
Sellers Robert
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