Method for suppressing solvent resonance signals in NMR experime

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

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G01R 3320

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active

055325947

ABSTRACT:
B.sub.1 (RF) gradient echo pulse sequences are combined with frequency-selective pulse sequences to selectively suppress a solvent resonance signal by preventing the formation of an echo for the solvent resonance, while allowing the formation of an echo for the sample resonances under study. The RF gradient pulses may be planar or radial pulses. A pulse sequence for suppressing a solvent resonance signal in NMR experiments comprises a pair of (RF) gradient pulses which sandwich a selective inversion pulse sequence. In accordance with one embodiment of the invention, the RF gradient pulses are anti-symmetric (have opposite phase) and the selective inversion pulse sequence comprises a homogeneous frequency-selective inversion pulse, such as a .pi. pulse, applied in time between the two RF gradient pulses. In accordance with another embodiment of the invention, the RF gradient pulses are symmetric (have the same phase) and the selective inversion pulse sequence comprises a pulse sequence which has an excitation profile with a null at the frequency of the resonance to be suppressed.

REFERENCES:
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patent: 5204626 (1993-04-01), Onodera et al.
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patent: 5283526 (1994-02-01), Spielman et al.
patent: 5327085 (1994-07-01), Cory
Bax et al, "Separation of the Different orders of NMR Multiple Quantum transitions by the use of pulsed field Gradients" Chemical Physics Letters vol. 69 No. 3 pp. 567-570 1 Feb. 1980.

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