Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1977-02-18
1978-11-07
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424317, 424337, A61K 3122
Patent
active
041247230
ABSTRACT:
A method for suppressing the release of histamine from sensitized leukocytes in warm blooded animals which comprises administering internally to said animals compounds of the formula: ##STR1## wherein n is a whole integer from 1 to 4; X is halogen and Z is COOH, CH.sub.2 OR or ##STR2## R being a lower alkyl chain of from 1 to 6 carbon atoms and pharmaceutically acceptable salts of those compounds wherein Z is COOH, in sufficient amount to suppress the release of histamine from said cells.
REFERENCES:
patent: 3651236 (1972-03-01), Kelly et al.
patent: 3879544 (1975-04-01), Reisner et al.
Chemical Abstracts 67: 90489b (1967).
Berger Frank M.
Fukui George M.
Ludwig Bernard J.
Reisner David B.
Carter-Wallace Inc.
Clarke Kevin B.
Schenkman Leonard
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