Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2000-10-20
2011-11-01
Landsman, Robert (Department: 1647)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C435S335000, C435S343000
Reexamination Certificate
active
08048855
ABSTRACT:
A method for effectively suppressing GVHD, which occurs after peripheral blood stem cells allotransplantation, without causing marked side effects, and a pharmaceutical composition intended for this purpose and containing human G-CSF as an active ingredient. GVHD can be suppressed by administering human G-CSF to a transplantation recipient after peripheral blood stem cells transplantation.
REFERENCES:
patent: 5800539 (1998-09-01), Waller
patent: 5806529 (1998-09-01), Reisner et al.
patent: 5880090 (1999-03-01), Hammond et al.
patent: 6162427 (2000-12-01), Baumann et al.
Martin et al. Haematologica, 1996 81:464-467.
Kokai et al. Artificial Organs, 1996 20(8):883-889.
Iizuka et al. Blood, 1997 89(4):1446-1451.
Bishop et al., A randomized, double-blind trial of filgrastim (granulocyte colony-stimulating factor) versus placebo following allogeneic blood stem cell transplantation, Jul. 2000, vol. 96, Issue 1, pp. 80-85.
Bork et al., Go hunting in sequence databases but watch out for the traps, 1996, Trends in Genetics, vol. 12, pp. 425-427.
Bork, Powers and Pitfalls in Sequence Analysis: the 70% hurdle, 2000, Genome Research, vol. 10, pp. 398-400.
Brenner, Errors in genome annotation, 1999, Trends in Genetics, vol. 15, pp. 132-132.
Doerks et al., Protein annotation: detective work for function prediction, 1998, Trends in Genetics, vol. 14, pp. 248-250.
Ngo et al., The protein folding problem and tertiary structure prediction,1994, pp. 492-495.
Skolnick et al., From genes to protein structure and function: novel applications of computational approaches in the genomic era, 2000, Trends in Biotech, vol. 18, Issue 1, pp. 34-39.
Smith et al., The challenge of genome sequence annotation or “the devil is in the details”, 1997, Nature Biotechnology, vol. 15, pp. 1222-1223.
Wells et al., Addivity of mutational effects in proteins, 1990, Biochemistry, vol. 29, pp. 8509-8517.
M. Hirokawa et al., “Modulation of Allogeneic Immune Responses by Filgrastim (Recombinant Human Granulocyte Colony-Stimulating Factor) In Bone Marrow Transplantation”,Chemical Abstracts, vol. 124, No. 17, abstract No. 221547q, (1996).
O. Ringden et al., “Peripheral Blood Stem Cell Transplantation From Unrelated Donors: A Comparison With Marrow Transplantation”,Blood, vol. 94, No. 2, pp. 455-464 (Jul. 15, 1999).
A. M. Marmont et al., “T-Cell Depletion of HLA-Identical Transplants in Leukemia”,Blood, vol. 78, No. 8, pp. 2120-2130 (Oct. 15, 1991).
M. Hirokawa et al., “Modulation of Allogeneic Immune Responses by Filgrastim (Recombinant Human Granulocyte Colony-Stimulating Factor) In Bone Marrow Transplantation”,International Journal of Hematology, vol. 62, pp. 235-241 (1995).
M.J. Pittet et al., “Cutting Edge: Cytolytic Effector Function in Human Circulating CD8+T Cells Closely Correlates with CD56 Surface Expression”,The Journal of Immunology, pp. 1148-1152 (2000).
S.E. Theocharis et al., “Effect of Two Forms of Granulocyte-Colony-Stimulating Factor on Hepatic Regeneration After 70% Partial Hepatectomy in Rats”,Clinical Science, vol. 92, pp. 315-320 (1997).
M. Mielcarek et al., “Suppression of Alloantigen-Induced T-Cell Proliferation by CD14+Cells Derived from Granulocyte Colony-Stimulating Factor—Mobilized Peripheral Blood Mononuclear Cells”,Blood, vol. 89, No. 5, pp. 1629-1634 (Mar. 1, 1997).
C.R. Kusnierz-Glaz et al., “Granulocyte Colony-Stimulating Factor-Induced Comobilization of CD431CD8−T Cells and Hematopoietic Progenitor Cells (CD34+) in the Blood of Normal Donors”,Blood, vol. 89, No. 7, pp. 2586-2595 (Apr. 1, 1997).
D. Zeng et al., “Granulocyte Colony-Stimulating Factor Reduces the Capacity of Blood Mononuclear Cells to Induce Graft-Versus-Host Disease: Impact on Blood Progenitor Cell Transplantation”,Blood, vol. 90, No. 1, pp. 453-463 (Jul. 1, 1997).
B.M. Snadmaier et al., “Allogeneic Transplants of Canine Peripheral Blood Stem Cells Mobilized by Recombinant Canine Hematopoietic Growth Factor”,Blood, vol. 87, No. 8, pp. 3508-3513 (Apr. 15, 1996).
T. Pollmächer et al., “Effects of granulocyte Colony-Stimulating Factor on Plasma Cytokine and Cytokine Receptor Levels and on the In Vivo Host Response to Endotoxin in Healthy Men”,Blood, vol. 87, No. 3., pp. 900-905 (Feb. 1, 1996).
L. Pan et al., “Pretreatment of Donor Mice With Granulocyte Colony-Stimulating Factor Polarizes Donor T Lymphocytes Toward Type-2 Cytokine Production and Reduces Severity of Experimental Graft-Versus-Host Disease”,Blood, vol. 86, No. 12, pp. 4422-4429 (Dec. 15, 1995).
T. Hartung et al., “Effect of Granulocyte Colony-Stimulating Factor Treatment on Ex Vivo Blood Cytokine Response in Human Volunteers”,Blood, vol. 85, No. 9, pp. 2482-2489 (May 1, 1995).
J. Tanaka et al., “The Role of Accessory Cells in Allogeneic Peripheral Blood Stem Cell Transplantation”,International Journal of Hematology, vol. 69, pp. 70-74 (1999).
P.F. Foster et al., “The Use of Granulocyte Colony-Stimulating Factor After Liver Transplantation”,Transplantation, vol. 59, No. 11, pp. 1557-1563 (Jun. 15, 1995).
R.A. Mann et al., “CD8+, Radiosensitive T Cells of Parental Origin, Oppose Cells Capable of Down-Regulating Cytotoxicity in Murine Acute Lethal Graft-Versus-Host Disease”,Clinical Immunology and Immunopathology, vol. 89, No. 3, pp. 260-270 (Dec. 1998).
R.D. Allen et al., “Genetics of Graft-Versus-Host Disease, I. A Locus on Chromosome 1 Influences Development of Acute Graft-Versus-Host Disease in a Major Histocompatibility Complex Mismatched Murine Model”,Immunology, vol. 96, pp. 254-261 (1999).
S. Quaranta et al., “Autoantibodies in Human Chronic Graft-Versus-Host Disease After Hematopoietic Cell Transplantation”,Clinical Immunology, vol. 91, No. 1, pp. 101-116 (Apr. 1999).
G.R. Brown et al., “Tumor Necrosis Factor Inhibitor Ameliorates Murine Intestinal graft-Versus-Host Disease”,Gastroenterology, vol. 116, No. 3, pp. 593-601 (1999).
K. Saigo et al., “Therapeutic Strategy for Post-Transfusion Graft-Vs.-Host Disease”,International Journal of Hematology, pp. 147-151 (1998).
O. Ringden et al., “Increased Risk of Chronic Graft-Versus-Host Disease, Obstructive Bronchiolitis, and Alopecia With Busulfan Versus Total Body Irradiation: Long-Term Results of a Randomized Trial in Allogeneic Marrow Recipients With Leukemia”,Blood, vol. 93, No. 7, pp. 2196-2201 (Apr. 1, 1999).
R.J. Jones et al., “Induction of Graft-Versus-Host Disease After Autologous Bone Marrow Transplantation”,Blood, vol. 89, No. 6, pp. 754-756 (1997).
A. D. Hess et al., “Specificity of Effector T Lymphocytes in Autologous Graft-Versus-Host Disease: Role of the Major Histocompatibility Complex Class II Invariant Chain Peptide”,Blood, vol. 89, No. 6, pp. 2203-2209 (Mar. 15, 1997).
J.L.M. Ferrara et al., “Graft-Versus-Host Disease”,The New England Journal of Medicine, vol. 324, No. 10, pp. 667-674 (1991).
G. Eberl et al., “Tissue-Specific Segregation of CD1d-Dependent and CD1d-Independent NK T Cells”,The Journal of Immunology, pp. 6410-6419 (1999).
M.R. Bishop et al., “A Randomized, Double-Blind Trial of Filgrastim (Granulocyte Colony-Stimulating Factor) Versus Placebo Following Allogeneic Blood Stem Cell Transplantation”,Blood, vol. 96, No. 1, pp. 80-85 (Jul. 1, 2000).
J. Contreras et al., “Mobilized Recipient CD34+Cells Promote Acceptance of Incompatible Primate Allografts Without Immunosuppression”,American Society of Transplantation, AST Eighteenth Annual Mtg., (1999).
K. Iizuka et al., “Host F1 Mice Pretreated With Granulocyte Colony-Stimulating Factor Accept Parental Bone Marrow Grafts In Hybrid Resistance System”,Blood, vol. 89, No. 4, pp. 1446-1451 (Feb. 15, 1997).
K.J.L. Hammond et al., “NKT Cells are Phenotypically and Functionally Diverse”,Eur. J. Immunol., vol. 29, pp
Kataoka Motoyuki
Yamamoto Kaname
Chugai Seiyaku Kabushiki Kaisha
Dang Ian
Landsman Robert
LandOfFree
Method for suppressing graft-versus-host-disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for suppressing graft-versus-host-disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for suppressing graft-versus-host-disease will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4292321