Method for sulfonation of 1,2-benzisoxazole-3-acetic acid

Details Method for sulfonation of 1,2-benzisoxazole-3-acetic acid Method for sulfonation of 1,2-benzisoxazole-3-acetic acid

2007-09-11

2007-09-11

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

11531364

ABSTRACT:
An efficient method for the preparation of 1,2-benzisoxazole-3-methanesulfonic acid involves a reaction of 1,2-benzisoxazole-3-acetic acid in toluene with chlorosulfonic acid optionally mixed with an inert solvent in the presence of a particular Lewis base (ester or a nitrile).

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