Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...
Patent
1999-05-03
2000-07-25
Shah, Mukund J.
Chemistry: molecular biology and microbiology
Differentiated tissue or organ other than blood, per se, or...
435 12, 435 13, 435325, 435366, 436 18, C12N 500, C12N 502, G01N 3100
Patent
active
060935324
ABSTRACT:
The invention concerns novel benzisoselen-azoline and -azine derivatives. These novel derivatives have the following general formula (II): ##STR1## where: R.sup.1 to R.sup.8 and R.sup.10 have various meanings, in particular H, alkyl, etc . . . ; ##STR2## Y.sup.- represents the anion of a pharmaceutically acceptable anion; n=0, 1; m=0, 1, 2; p=1, 2, 3; q=2, 3, 4; r=0, 1; and their pharmaceutically acceptable salts of acids or bases; there being no more than one substituent R.sup.9 in each molecule with general formula II. These novel derivatives can be used in medication.
REFERENCES:
Yoshikawa et al., Cancer Research 33, 1617-1620, Apr. 1995.
Trush et al., Free Radical Biology & Medicine, vol. 10, pp 201-209, 1991.
Chaudiere Jean
Erdelmeier Irene
Moutet Marc
Yadan Jean-Claude
Kifle Bruck
Oxis Isle of Man, Limited
Shah Mukund J.
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