Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai
Patent
1991-03-21
1993-02-16
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
N-c doai
A01N 4710
Patent
active
051871939
ABSTRACT:
A process is provided for obtaining one or more bone marrow cell growth factors having granulocyte/macrophage progenitor cell colony stimulating activity, said process comprising: (a) adding to the culture medium of an in vitro, established bone marrow culture a growth factor-stimulating amount of a dithiocarbamate; (b) separating the said dithiocarbamate from the in vitro treated bone marrow culture, adding fresh culture medium to said in vitro treated bone marrow culture, and permitting the concentration of said growth factor or factors to increase in said fresh culture medium; and (c) isolating said growth factor or factors from said fresh culture medium.
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Borch Richard F.
Schmalbach Therese K.
Robinson Douglas W.
Saucier S.
University of Rochester
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