Method for stimulating connective tissue growth or wound...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S008100, C514S012200

Reexamination Certificate

active

07105481

ABSTRACT:
PDGF-D, a new member of the PDGF/VEGF family of growth factors, as well as the nucleotide sequence encoding it, methods for producing it, antibodies and other antagonists to it, transfected and transformed host cells expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications, including methods for stimulating growth of a connective tissue or healing a wound in a mammal, which methods comprise administering to the mammal an effective amount of PDGF-D polypeptides or polynucleotides encoding the PDGF-D polypeptides.

REFERENCES:
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patent: WO 96/27007 (1996-09-01), None
patent: WO 00/34474 (2000-06-01), None
patent: WO 00/66736 (2000-11-01), None
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Voet et al. Biochemistry John Wiley & Sons, Inc., pp. 126-128 and 228-234.
Database GENCORE on EST, AN AA488780, NCI-CGAP, National Cancer Institute, Cancer Genome Anatomy Project (CGAP), Tumor Gene Index. Gene Sequence, Aug. 15, 1997.
Database GENCORE on EST, AN AA488996, NCI-CGAP, National Cancer Institute, Cancer Genome Anatomy Project (CGAP), tumor Gene Index, Gene Sequence, Aug. 15, 1997.
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Database GENCORE on EST, AN AQ041639, Adams et al. Use of a random BAC End Sequence Database for Sequence-Ready Map Building (1998), Gene Sequence, Jul. 14, 1998.
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Miyama et al., Moleuclar Cloning and Functional Expression of a cDNA Encoding Glycosylation-Inhibiting Factor, 1993, Proc. Natl. Acad. Sci., pp. 10056-10060, vol. 90, USA.
Voet et al., “Biochemistry”, pp. 126-128 and pp. 228-234, John Wiley & Sons, Inc.

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