Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Albumin
Patent
1994-10-26
1997-11-25
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Albumin
530362, 530364, 435 691, 435 696, 435 701, 435 711, C07K 100, C12P 2106
Patent
active
056914512
ABSTRACT:
A recombinant human serum albumin (rHSA) pharmaceutical preparation is sterilized by subjecting a pharmaceutical preparation of rHSA obtained by gene manipulation techniques packed in a container in an administration unit to heat treatment at 50.degree. to 80.degree. C. for 30 minutes or more. By the disclosed method, rHSA having high safety can be provided since microorganisms contaminated in rHSA pharmaceutical preparations die as a result of the sterilization method of the present invention.
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Dengler et al, Chemical Abstracts, vol. 112, p. 274, Ref. #118203. 1990 (Infusiontherapie, 1989, 16(4), 160-164).
Kobayashi Kaoru
Kuwae Shinobu
Ohda Toyoo
Ohmura Takao
Ohya Tomoshi
Mohamed Abdel A.
The Green Cross Corporation
Tsang Cecilia J.
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