Method for sterilizing bone grafts

Details Method for sterilizing bone grafts Method for sterilizing bone grafts

1995-04-07

1997-01-07

Warden, Robert J.

Chemical apparatus and process disinfecting, deodorizing, preser

Process disinfecting, preserving, deodorizing, or sterilizing

Using fluent heat transfer medium other than air

422 40, 435 13, 623 16, A61L 204, A01N 102, A61F 228

Patent

active

055913989

ABSTRACT:
A method and apparatus for sterilizing bone grafts, wherein the bone graft together with a quantity of sterile liquid sufficient to cover the bone graft is initially heated at a given sterilizing temperature for a constant first period of time, and is subsequently heated for a variable second period of time the duration of which is a function of the size of the bone graft. The bone graft is then cooled to room temperature, and the liquid transferred to a container. The sterilized bone graft is frozen, and the liquid in the container is analyzed for infectious diseases.

REFERENCES:
patent: 3987791 (1976-10-01), Chittenden et al.
patent: 4994237 (1991-02-01), Login et al.
patent: 5122344 (1992-06-01), Schmoegner
patent: 5429810 (1995-07-01), Knaepler et al.
H. Knaepler, S. Laubach & L. Gotzen, Die Knochenbank--Standardisiertes Verfahren?, Chirurg (1990) 61: pp. 833-836.
H. Knaepler et al, Experimentelle Untersuchungen zur thermischen Desinfektion und Sterilisation allogener Knochentransplantate, Unfallchirung (1992) 95: pp. 1-8.

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