Method for stabilizing rubella HA antigen

Details Method for stabilizing rubella HA antigen Method for stabilizing rubella HA antigen

1985-10-28

1987-09-01

Foelak, Morton

Drug, bio-affecting and body treating compositions

Lymphokine

424 89, 530412, A61K 3900

Patent

active

046908196

ABSTRACT:
A method for stabilizing rubella HA antigen which comprises adjusting a rubella HA antigen suspension at pH 9.6 or higher, and more preferably, concurrently adding sodium azide thereto, or adding sodium azide alone at a concentration of 1 to 10% (w/v) thereto without the above adjustment of pH.

REFERENCES:
patent: 3553312 (1971-01-01), Delgado
patent: 4195074 (1980-03-01), Safford
patent: 4590156 (1986-05-01), Dorsett
Chong et al., "Purification of Biologically Active Rubella Virus Antigen . . . Chromatography" J. Virol. Methods 10 (1985) pp. 261-268.

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