Method for stabilizing menthyl lactate

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

Reexamination Certificate

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C560S179000

Reexamination Certificate

active

07655816

ABSTRACT:
A method for stabilizing menthyl lactate is disclosed. The method comprises combining water with a solution comprising menthyl lactate and a water-miscible organic solvent in amounts effective to precipitate menthyl lactate from the resulting aqueous mixture. The aqueous precipitation method is simple to practice, and it provides menthyl lactate having remarkably improved storage stability.

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patent: 2006/0165783 (2006-07-01), Korber
Ojima, et al., “Reduction of Carbonyl Compounds via Hydrosilylation. 3. Asymmetric Reduction of Keto Esters via Hydrosilylation Catalyzed by a Rhodium Complex with Chiral Phosphine Ligands”,Journal of Organic Chemistry, 42(10), 1977 pp. 1671-1679.
Boireau, et al., “Highly Diastereoselective Reduction of (−) methylphenylglyoxalate and (—) menthylpyruvate Using New Hindered Lithiumtrialkoxyaluminohydrides”,Tetrahedron: Asymmetry, vol. 2(8), pp. 771-774,1991.

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