Method for stabilizing macrolide compounds

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Reexamination Certificate

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C536S007100

Reexamination Certificate

active

07655442

ABSTRACT:
The present invention provides a method for stabilizing a macrolide compound, and an efficient method for producing the compound. Specifically, it provides a method for stabilizing a macrolide compound, in which a 12-membered ring macrolide compound, such as a compound expressed by the formula (1) and a cyclodextrin are both present, and a method for producing a macrolide compound, in which a cyclodextrin is made to be present in a culture broth of actinomycetes having an ability of producing the macrolide compound.

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Koontz et al., J. Agric. Food Chem., vol. 51, No. 24, pp. 7111-7114, Oct. 15, 2003.

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