Method for stabilizing biomolecules in liquid formulations

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S003100, C514S053000, C514S054000

Reexamination Certificate

active

07141542

ABSTRACT:
The invention is directed to a stable formulation of a biologically active protein useful for aerosol delivery to the respiratory tract of a patient in need of treatment comprising:(a) a carrier liquid comprising from about 10% to from about 100% V/V water and from about 0% to from about 90% V/V of an organic liquid;(b) a biologically effective amount of a protein suspended or dissolved in a carrier liquid; and(c) a stabilizing effective amount of a derivatized carbohydrate stabilizing agent suspended or dissolved in said carrier liquid.The stable formulations of the invention may optionally contain about 0.1% to about 5.0% W/V of a pharmaceutically acceptable excipient.

REFERENCES:
patent: 4659012 (1987-04-01), Coffee
patent: 4829996 (1989-05-01), Noakes
patent: 4851211 (1989-07-01), Adjei et al.
patent: 5385685 (1995-01-01), Humphreys et al.
patent: 5578567 (1996-11-01), Cardinaux
patent: 5653987 (1997-08-01), Modi et al.
patent: 5660166 (1997-08-01), Lloyd
patent: 5813614 (1998-09-01), Coffee
patent: 6105571 (2000-08-01), Coffee
patent: 6105877 (2000-08-01), Coffee
patent: 6123068 (2000-09-01), Lloyd
patent: 6158431 (2000-12-01), Poole
patent: 6302331 (2001-10-01), Dvorsky
patent: 2003/0173219 (2003-09-01), Davies et al.
patent: 0-234-842 (1987-09-01), None
patent: 62473 (1993-05-01), None
patent: 51116806 (1976-10-01), None
patent: 818619 (1981-04-01), None
patent: WO 94/14543 (1994-07-01), None
patent: WO 95/26235 (1995-10-01), None
patent: WO 98/29097 (1998-07-01), None
patent: WO 99/01463 (1999-01-01), None
patent: WO 99/07478 (1999-02-01), None
patent: WO 99/33853 (1999-07-01), None
patent: WO 99/42153 (1999-08-01), None
patent: WO 99/49981 (1999-10-01), None
patent: WO 00/35524 (2000-06-01), None
patent: WO 00/38770 (2000-07-01), None
patent: WO 00/66206 (2000-11-01), None

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for stabilizing biomolecules in liquid formulations does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for stabilizing biomolecules in liquid formulations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for stabilizing biomolecules in liquid formulations will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3665440

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.