Cleaning compositions for solid surfaces – auxiliary compositions – Cleaning compositions or processes of preparing – For cleaning a specific substrate or removing a specific...
Patent
1994-02-07
1996-07-02
Lieberman, Paul
Cleaning compositions for solid surfaces, auxiliary compositions
Cleaning compositions or processes of preparing
For cleaning a specific substrate or removing a specific...
134 18, 134 30, 134 42, 422 28, 435184, 435188, 510393, 510530, C11D 3386
Patent
active
055319173
ABSTRACT:
A method for stabilizing an agent for contact lenses containing a proteolytic enzyme by adding a surfactant to a solution containing an effective amount of a proteolytic enzyme, the production of a lyophilized agent for contact lenses containing a proteolytic enzyme, which comprises subjecting an aqueous composition containing a proteolytic enzyme to a lyophilizing treatment in the presence of a surfactant, and a lyophilized agent for contact lenses which contains a proteolytic enzyme and a surfactant. The method of the present invention enables stable preservation of a proteolytic enzyme in a liquid form. In addition, cleaning, sterilization and preservation can be simultaneously performed with a single solution, wherein an efficient removal of soil is achieved by only immersing contact lenses in the agent in a solution state. Accordingly, the agent of the present invention is advantageously used with ease by simple handling. The method for producing the lyophilized agent of the present invention enables stabilization of a proteolytic enzyme during preparation into a lyophilized formulation. Furthermore, the lyophilized agent of the present invention permits the proteolytic enzyme to remain stable and is extremely superior in solubility. When preserved as an aqueous solution, the stability of the enzyme can be maintained over a long period of time due to the action of a surfactant contained therein.
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Kimoto Akihiro
Nakayama Hisayuki
Tsuchino Kuniko
Fries Kery
Lieberman Paul
Senju Pharmaceutical Co. Ltd.
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