Method for stabilizing a tumor necrosis factor and a stable aque

Details Method for stabilizing a tumor necrosis factor and a stable aque Method for stabilizing a tumor necrosis factor and a stable aque

1983-03-23

1984-05-08

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112R, 260117, 260121, 424101, 424177, C07G 700

Patent

active

044473559

ABSTRACT:
A method for stabilizing a Tumor Necrosis Factor (TNF), which comprises adding at least one member selected from the group consisting of an albumin, a gelatin, a globulin, a protamine and a salt of protamine to an aqueous solution or powder containing TNF, and a stable aqueous solution or powder which contains TNF and an effective amount of such a protein. The aqueous solution or powder containing TNF can be stored for a prolonged period of time without losing its activity, and is stable on freezing, thawing, lyophilization or the like.

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