Method for solubilization of aspartame in effervescent aqueous s

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Gas produced in situ by chemical reaction

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424156, 424466, A61K 946, A61K 962, A61K 3310

Patent

active

047833319

ABSTRACT:
A method and composition for providing aspartame as a sweetener in effervescent calcium ion-generating systems is provided. The method includes a step for providing a selected surfactant in association with the aspartame sweetener, to provide for aqueous solution of the aspartame in the presence of the solubilized calcium without film formation and without excessive foaming. Preferably, the aspartame/surfactant is provided by a granule composition, utilized in association with a calcium carbonate/citric acid effervescent couple.

REFERENCES:
patent: 4083950 (1978-04-01), Duvall et al.
patent: 4650669 (1987-03-01), Alexander et al.
patent: 4680323 (1987-07-01), Lowey
patent: 4704269 (1987-11-01), Korab
Ivanovich et al., "The Absorption of Calcium Carbonate", Annals of Internal Medicine, vol. 66, No. 5, pp. 917-923, (May 1967).

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