Method for solubilization and naturation of somatotropins

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.

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530412, 530418, 530425, 530426, C07K 300

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active

060342242

ABSTRACT:
A method for the solubilization and/or naturation of a somatotropin involves contacting a somatotropin with a detergent composition and water under conditions effective to obtain a naturated somatotropin, wherein the detergent composition may be a C.sub.10, C.sub.12, C.sub.16 or C.sub.18 acyl glutamate, a C.sub.10, C.sub.14 or C.sub.18 alkyl sulfate, an alcohol ethoxy sulfate, lauroyl ethylenediamine-triacetic acid (LEDA), a C.sub.10 to C.sub.18 linear alkyl benzene sulfonate, diphenyl disulfonate or an acyl amino acid.

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