Method for site-specific integration of nucleic acids and relate

Details Method for site-specific integration of nucleic acids and relate Method for site-specific integration of nucleic acids and relate

1998-04-17

1999-06-29

McKelvey, Terry

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

435243, 4353201, 435410, 536 234, C12N 510, C12N 100, C12N 1562, C12N 1563

Patent

active

059168048

ABSTRACT:
Chimeric proteins are provided comprising a first domain that attaches said chimeric protein to a target nucleic acid, and a second domain that integrates donor nucleic acid into a target nucleic acid. Also provided are nucleic acid constructs, recombinant vectors encoding invention chimeric proteins, recombinant retroviruses, and related methods.

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