Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-09-12
1997-12-09
Fleisher, Mindy
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 4351723, 536 221, 536 242, 536 243, 935 1, 935 5, 935 6, 935 8, 935 9, 935 16, 935 19, C12Q 0168, C12P 1934, C12N 1500, C07H 2100
Patent
active
056959370
ABSTRACT:
Serial analysis of gene expression, SAGE, a method for the rapid quantitative and qualitative analysis of transcripts is provided. Short defined sequence tags corresponding to expressed genes are isolated and analyzed. Sequencing of over 1,000 defined tags in a short period of time (e.g., hours) reveals a gene expression pattern characteristic of the function of a cell or tissue. Moreover, SAGE is useful as a gene discovery tool for the identification and isolation of novel sequence tags corresponding to novel transcripts and genes.
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Kinzler Kenneth W.
Velculescu Victor E.
Vogelstein Bert
Zhang Lin
Fleisher Mindy
The Johns Hopkins University School of Medicine
Weiss Bonnie D.
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