Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1991-05-08
1993-08-10
Rosen, Sam
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 79, 435 792, 435 794, 435 795, 436512, 436518, 436540, 436543, 436538, C12Q 100, G01N 33535
Patent
active
052348121
ABSTRACT:
The invention relates to an assay for determining an analyte in a fluid sample. Three receptors are used, with formation of a quaternary or four member complex. One of the receptors is bound to a solid phase, and binds to complexes of another receptor and the analyte. A third receptor is labelled, and it, too, binds analyte. The invention also involves the use of a displacement solution to wash fluid sample from solid phase after the first portion of the quaternary complex forms, i.e., prior to binding with the labelled receptor.
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Oellerich, J. Clin. Chem. Biochem. 18: 197-199 (1980).
Berger Hans
Buck Harvey
DeLaCroix Fern
Boehringer Mannheim Corporation
Rosen Sam
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