Method for separation of nucleated fetal erythrocytes from mater

Liquid purification or separation – Processes – Separating

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204450, 204518, 204543, 210767, 435 2, 436175, 436177, 436178, G01N 2726, G01N 3349, B01D 3700

Patent

active

056628137

ABSTRACT:
A charge-flow separation apparatus (CFS) and method for enriching rare cell populations, particularly fetal cells, from a whole blood sample by separating the rare cell fractions from whole according to the relative charge density and/or the relative binding affinity for a leukocyte depletion solid phase matrix. The enrichment method may be operated stand alone, or as a pre- or post-processing step in conjunction with a charge-flow separation method.

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