Method for separating long-chain nucleic acids

Details Method for separating long-chain nucleic acids Method for separating long-chain nucleic acids

1987-11-23

1991-10-15

Rosen, Sam

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Treating animal or plant material or micro-organism

536 27, 536 28, C12N 108, C07H 1512

Patent

active

050574264

ABSTRACT:
A method for the separation of long-chain nucleic acids from other substances in solutions containing nucleic acids and other materials, comprising fixing long-chain nucleic acids in a nucleic acid-containing solution onto a porous matrix, washing the porous matrix to separate the other substances from the long-chain nucleic acids, and removing the fixed long-chain nucleic acids from the porous matrix is disclosed. A device for carrying out the method of the claimed invention is also described.

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Pharmacia, FPLC: Media and Column Guide, "High Performance Separation of Biomolecules", pp. 1-16.
Jandera et al., "Gradient Elution in Column Liquid Chromatography", Journal of Chromatography Library, vol. 31, pp. 381-393, 1985.
Mikes, "High-Performance Liquid Chromatography of Biopolymers and Biooligomers", Journal of Chromatography Library, vol. 41B, pp. B180-189, B200-211.

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