Method for separating lactone-containing high-molecular...

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

Reexamination Certificate

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C210S656000, C549S263000

Reexamination Certificate

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06881341

ABSTRACT:
A method for separating a lactone-containing high-molecular weight compound comprising subjecting a mixture of a lactone-containing high-molecular weight compound having, as its side-chain, at least one of a lower alkenyl group and a lower alkoxy group and its analogous compound(s) to either one or both steps in any order of a step (A) for adsorbing the mixture to a nonionic adsorption resin and eluting with an aqueous solvent containing silver ions, and a step (B) for adsorbing the mixture to a basic active alumina and eluting with an organic solvent to separate each of the compounds.

REFERENCES:
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patent: 6576135 (2003-06-01), Higaki et al.
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patent: 2 157 682 (1985-10-01), None
patent: 03 191788 (1991-08-01), None
H. Oka, et al., “Separation of Antibodies by Counter-Current Chromatography”,Journal of Chromatography A., vol. 812, No. 1-2, pp. 35-52.
W. Wang-Fan, et al., “Application of Centrifugal Counter-Current Chromatography to the Separation of Macrolide Antibiotic Analogues”,Journal of Chromatography A., 1999, vol. 864, pp. 69-76.

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