Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge
Patent
1992-10-20
1994-11-22
Niebling, John
Chemistry: electrical and wave energy
Processes and products
Electrostatic field or electrical discharge
2504611, 356344, 356412, B01D 5702
Patent
active
053666011
ABSTRACT:
A technique for separating, identifying and measuring ions in solution by capillary zone electrophoresis is described, which provides improved sensitivity and resolution of anionic species. The method involves introducing a sample containing the ionic species into a narrow bore capillary filled with a carrier electrolyte containing a selected light-absorbing anion. An electrical potential is applied across the capillary column causing the ions to elute according to their ionic mobility. Both UV absorbing and UV-transparent ions can be detected and quantitated by UV/visible photometric monitoring.
REFERENCES:
patent: 4414842 (1983-11-01), Small et al.
patent: 4936974 (1990-06-01), Rose et al.
patent: 5104506 (1992-04-01), Jones et al.
patent: 5128005 (1992-07-01), Jones et al.
patent: 5156724 (1992-10-01), Jones et al.
Burgi et al., "Capillary Electrophoresis of Anions with High Mobilities Uses Diethylene Triamine to Suppress Electro-Osmotic Flow with Sample Injected at Negative Electrode," Research Disclosure 340016, Derwent WPI, Acc. No.: 92-305906/37, Aug. 10, 1992.
X. Huang et al., "Quantitative Analysis of Low Molecular Weight Carboxylic Acids by Capillary Zone Electrophoresis/Conductive Detection", Anal. Chem., 61: 766-770 (1989).
F. Foret et al., "Indirect Photometric Detection in Capillary Zone Electrophoresis", J. Chromatography, 470: 299-308 (1989).
W. G. Kuhr and E. S. Yeung, "Optimization of Sensitivity and Separation in Capillary Zone Electrophoresis with Indirect Fluorescence Detection", Anal. Chem., 60: 2642-2646 Dec. 1988.
W. G. Kuhr and E. S. Yeung, "Indirect Fluorescence Detection of Native Amino Acids in Capillary Zone Electrophoresis", Anal. Chem., 60: 1832-1834 (1988).
T. Takeuchi et al., "Indirect Fluorometric Detection in Micro High-Performance Liquid Chromatography", Chromatographia, 25: 1072-1074 Dec. 1988.
K. D. Altria and C. F. Simpson, "High Voltage Capillary Zone Electrophoresis: Operating Parameters Effects on Electroendosmotic Flows and Electrophoretic Mobilities", Chromatographia, 24: 527-532 (1987).
T. Tsuda et al., "Separation of Organic and Metal Ions by High-Voltage Capillary Electrophoresis", J. Chromatography, 264: 385-392 (1983).
J. W. Jorgenson and K. D. Lukacs, "Capillary Zone Electrophoresis", Science, 222: 266-272 Oct. 1983.
F. Foret et al., "On-Line Fiber Optic UV Detection Cell and Conductivity Cell for Capillary Zone Electrophoresis", Electrophoresis, 7: 430-432 (1986).
A. Nardi et al., "Capillary Zone Electrophoretic Separation of Cyclodextrins with Indirect UV Photometric Detection", Electrophoresis, 11: 774-776 (1990).
F. Foret et al., "Capillary Zone Electrophoresis of Rare Earth Metals with Indirect UV Absorbance Detection", Electrophoresis, 11: 780-783 (1990).
Jandik Petr
Jones William R.
Delacroix-Muirheid C.
Millipore Corporation
Niebling John
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