Method for selective methylation of erythromycin A derivatives

Details Method for selective methylation of erythromycin A derivatives Method for selective methylation of erythromycin A derivatives

1985-04-05

1987-06-09

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 75, C07H 1708

Patent

active

046721096

ABSTRACT:
A method for the selective methylation of a hydroxy group at the 6-position of an erythromycin A derivative which comprises converting an erythromycin A derivative into an erythromycin A 9-oxime derivative, and reacting the resulting ethythromycin A 9-oxime derivative with an methylating agent.

REFERENCES:
patent: 4331803 (1982-05-01), Watanabe et al.
patent: 4476298 (1984-10-01), Morimoto et al.
patent: 4496717 (1985-01-01), Adachi et al.

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