Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...
Reexamination Certificate
2007-04-05
2010-12-07
Belyavskyi, Michail A (Department: 1644)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Animal cell, per se, expressing immunoglobulin, antibody, or...
Reexamination Certificate
active
07846724
ABSTRACT:
The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof.
REFERENCES:
patent: 5202238 (1993-04-01), Fell et al.
patent: 5204244 (1993-04-01), Fell et al.
patent: 5610297 (1997-03-01), Powers
patent: 5770429 (1998-06-01), Lonberg et al.
patent: 7432359 (2008-10-01), Kataoka et al.
patent: 2003/0165502 (2003-09-01), Fujita-Yamaguchi
patent: 2004/0018191 (2004-01-01), Wang et al.
patent: 2005/0084906 (2005-04-01), Goetsch et al.
patent: 2005/0249730 (2005-11-01), Goetsch et al.
patent: 2008/0014203 (2008-01-01), Hansen et al.
patent: 1176195 (2002-01-01), None
patent: WO 87/05330 (1987-09-01), None
patent: 94/11026 (1994-05-01), None
patent: WO 95/14930 (1995-06-01), None
patent: WO 98/22136 (1998-05-01), None
patent: WO 99/51642 (1999-10-01), None
patent: WO 99/54342 (1999-10-01), None
patent: 00/61739 (2000-10-01), None
patent: WO 01/14424 (2001-03-01), None
patent: WO 02/053596 (2002-07-01), None
patent: WO 03/059951 (2003-07-01), None
patent: 03/106621 (2003-12-01), None
patent: WO 03/100008 (2003-12-01), None
patent: 2004/071529 (2004-08-01), None
patent: 2004/083248 (2004-09-01), None
patent: WO 2004/087756 (2004-10-01), None
patent: WO 2005/005635 (2005-01-01), None
patent: 2005/016967 (2005-02-01), None
patent: 2005/016970 (2005-02-01), None
patent: WO 2005/023872 (2005-03-01), None
patent: 2005/058967 (2005-06-01), None
patent: 2005/082415 (2005-09-01), None
patent: 2005/094376 (2005-10-01), None
patent: 2006/008639 (2006-01-01), None
patent: 2006/013472 (2006-02-01), None
Boerner et al., J. Immunol., 147, pp. 86-95 (1991).
Bruggemann et al., Year Immunol., 7, pp. 33-40 (1993).
Cole et al., Monoclonal Antibodies and Cancer Therapy, Alan R. Liss, pp. 77 (1985).
Hoogenboom et al., J. Mol. Biol., 227, pp. 381-388 (1992).
Jakobovits et al., Nature, 362, pp. 255-258 (1993).
Jakobovits et al., Proc. Natl. Acad. Sci, USA, 90, pp. 2551-2555 (1993).
Johnson et al., Nucleic Acids Res., 28, pp. 214-218 (2000).
Kane et al., Gene, 84, pp. 439-446 (1989).
Kolkekar et al., Biochemistry, 36, pp. 10901-10909 (197).
Makrides, S.C., Protein Expr. Purif., 17, pp. 183-202 (1999).
Marks et al., J. Mol. Biol., 222, pp. 581-597 (1991).
Mori, T., Biotech. Bioeng., 88, pp. 901-908 (2004).
Morrison et al., Proc. Natl. Acad. Sci. USA, 81, pp. 6851-6855 (1984).
Neuberger et al., Nature, 314, pp. 268-270 (1985).
Thelander et al., EMBO J., 8, pp. 2475-2479 (1989).
Urlaub et al., Cell, 33, pp. 405-412 (1983).
Urlaub et al., Somat. Cell Mol., Genet., 12, pp. 555-566 (1986).
Van Dijk et al., Curr. Opin. Chem. Biol., 5, pp. 368-374 (2001).
Werner, R.G., Drug Res., 48, pp. 870-880 (1998).
U.S. Appl. No. 11/784,029, Office Action dated Aug. 6, 2008.
U.S. Appl. No. 11/784,029, Office Action dated Mar. 18, 2009.
Ito et al., J. Virol., 74, pp. 9300-9305 (2000).
Stabila et al., Nature Biotech, 16, pp. 1357-1360 (1998).
Routier et al., Glycoconjugate J., 14, pp. 201-207 (1997).
Niwa et al., J. Immunol. Methods, 306, pp. 151-160 (2005).
Mimura et al., J. Immunol Methods, 247, pp. 205-216 (2001).
Raju, T.S., BioProcess International, 1, pp. 44-53 (2003).
Ma, S., Anal. Chem., 71, pp. 5185-5192 (1999).
Fujii, S., J. Biol. Chem., 265, pp. 6009-6018 (1990).
Mizouchi et al., J. Immunol., 129, pp. 2016-2020 (1982).
Bergwerff et al., Glycoconjugate J., 12, pp. 318-330 (1995).
Nahrgang et al., Animal Cell Technology: Products from Cells, Cells as Products, Bernard et al. (eds), Kluwer Academic Publishers, Dordrecht, NL, pp. 259-261 (1999).
Lund et al., Mol. Immuno., 30, pp. 741-748 (1993).
Patel et al., Biochem. J., 285, pp. 839-845 (1992).
Davies et al., Biotechnol. Bioeng., 74, pp. 288-294 (2001).
Sheeley et al., Anal. Biochem, 247, pp. 102-110 (1997).
Shields et al., J. Biol. Chem., 277, pp. 26733-26740 (2002).
Zhu et al., Nature Biotechnol., 23, pp. 1159-1169 (2005).
Wright et al., Trends Biotechnol., 15, pp. 26-32 (1997).
Lifely et al., Glycobiology, 5, pp. 813-822 (1995).
Jefferis et al., Immunol. Rev., 163, pp. 59-76 (1998).
Bowie et al., Science, 247, pp. 1306-1310 (1990).
Flintoff et al., Somat. Cell Genet., 2, pp. 245-261 (1976).
Flintoff et al., Mol. Cell. Biol., 2, pp. 276-285 (1982).
Li et al., Cancer Immunology and Immunotherapy, 49, pp. 243-252, XP001113064 (2000).
Lubeck et al, The Journal of Immunology, 135(2), pp. 1299-1304 (1985).
Adams et al., Cell. Mol. Life Sci., 57, pp. 1050-1093 (2000).
Brüggemann et al., J. Exp. Med., 166, pp. 1351-1361 (1987).
Chen et al., EMBO J., 12, pp. 821-830 (1993).
Fishwild et al., Nat. Biotechnol., 14, pp. 845-851 (1996).
Lonberg et al., Nature, 368, pp. 856-859 (1994).
Love et al., Methods Enzymol., 178, pp. 515-527 (1989).
Riechmann et al., Nature, 332, pp. 323-327 (1988).
Schlaeger et al., Cytotechnology, 30, pp. 71-83 (1999).
Wilman, D.E.V., Prodrugs in Cancer Chemotherapy Biochemical Society Transactions, 14, pp. 375-383, 615thMeeting Belfast (1986).
Rohlik et al., Biochemical and Biophysical Research Communications, vol. 149, No. 1, pp. 276-281 (1987), XP008026319.
Hailey et al., Molecular Cancer Therapeutics, 1, pp. 1349-1353 (2002), XP008026465.
Pietrzkowski et al., Cell Growth Differ., 3, pp. 199-205 (1992).
Schnitzer, et al., European Journal of Cancer, Supplement, Pergamon, Oxford, GB, vol. 4, No. 12 (2006), XP005810433.
Benini, S., et al., Clin. Cancer Res., 7, pp. 1790-1797 (2001).
Bergmann, U., et al., Cancer Res., 55, pp. 2007-2011 (1995).
Brunetti, A., et al., Biochem. Biophys. Res. Commun., 165, pp. 212-218 (1989).
Delafontaine, P., et al., J. Mol. Cell. Cardiol., 26, pp. 1659-1673 (1994).
Dricu, A., et al., Glycobiology, 9, pp. 571-579 (1999).
Forsayeth, J. R., et al., Proc. Natl. Acad. Sci. USA, 84, pp. 3448-3451 (1987).
Gustafson, T. A., and Rutter, W. J., J. Biol. Chem., 265, pp. 18663-18667 (1990).
Hoyne, P. A., et al., FEBS Lett., 469, pp. 57-60 (2000).
Kalebic, T., et al., Cancer Res., 54, pp. 5531-5534 (1994).
Kanter-Lewensohn, L., et al., Melanoma Res., 8, pp. 389-397 (1998).
Kato, H., et al., J. Biol. Chem., 268, pp. 2655-2661 (1993).
Kull, F. C., J. Biol. Chem., 258, pp. 6561-6566 (1983).
Lammers, R., et al., EMBO J., 8, pp. 1369-1375 (1989).
Li, S. L., et al., Biochem. Biophys. Res. Commun., 196, pp. 92-98 (1993).
Morgan, D. O., and Roth, R. A., Biochemistry, 25, pp. 1364-1371 (1986).
O'Brien, R. M., et al., EMBO J., 6, pp. 4003-4010 (1987).
Pessino, A., et al., Biochem. Biophys. Res. Commun., 162, pp. 1236-1243 (1989).
Prigent, S. A., et al., J. Biol. Chem., 265, pp. 9970-9977 (1990).
Schaefer, E. M., et al., Biol. Chem., 265, pp. 13248-13253 (1990).
Scotlandi, K., et al., Cancer Gene Ther., 9, pp. 296-307 (2002).
Scotlandi, K., et al., Int. J. Cancer, 101, pp. 11-16 (2002).
Soos, M. A., et al., Proc. Natl. Acad. Sci. USA, 86, pp. 5217-5221 (1989).
Stella, V. J., et al., “Prodrugs: A Chemical Approach to Targeted Drug Delivery,” In: Directed Drug Delivery, Borchardt, R. T., et al., (eds.), pp. 247-267, Humana Press, Clifton, New Jersey (1985).
Surinya, K. H., et al., J. Biol. Chem., pp. 16718-16725 (2002).
Taylor, R., et al., Biochem. J., 242, pp. 123-129 (1987).
Tulloch, P. A., et al., J. Struct. Biol., 125, pp. 11-18 (1999).
Hansen Silke
Kuenkele Klaus-Peter
Reusch Dietmar
Schumacher Ralf
Belyavskyi Michail A
Hoffmann-La Roche Inc.
Johnston George W.
Rocha-Tramaloni Patricia S.
Wildman David E.
LandOfFree
Method for selecting CHO cell for production of glycosylated... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for selecting CHO cell for production of glycosylated..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for selecting CHO cell for production of glycosylated... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4235513