Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2004-05-11
2009-11-03
Ulm, John D (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S007210, C436S501000
Reexamination Certificate
active
07611848
ABSTRACT:
A method for identifying and selecting a compound acting as an allosteric regulator of a GPCR-III is described. A method comparing the activity level of a recombinant GPCR-III (GPCR-III-Δ), essentially depleted of the extracellular domain of the corresponding native GPCR-III, in the presence of a given compound, with the activity level of the same GPCR-III-Δ is described. A method of identifying positive or negative allosteric regulators of GPCRs-III is described.
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Gaven Florence
Goudet Cyril
Pin Jean-Philippe
Prezeau Laurent
Arent & Fox LLP
Centre National de la Recherche Scientifique "CNRS"
Ulm John D
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