Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-04-05
2011-04-05
Peng, Bo (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S070100, C435S328000, C530S387100, C530S387300, C530S388100, C530S389100, C424S136100, C436S547000
Reexamination Certificate
active
07919257
ABSTRACT:
The present invention provides combinations of specific binding proteins, such as immunoglobulins, that are designed to be true combinations, essentially all components of the combination being functional and compatible with each other. The invention further provides a method for producing a composition comprising at least two different proteinaceous molecules comprising paired variable regions, the at least two proteinaceous molecules having different binding specificities, comprising paired variable regions, at least two proteinaceous molecules having different binding specificities, comprising contacting at least three different variable regions under conditions allowing for pairing of variable regions and harvesting essentially all proteinaceous molecules having binding specificities resulting from the pairing.
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Hoogenboom Hendricus Renerus Jacobus Mattheus
Logtenberg Ton
Blumel Benjamin P
Merus Biopharmaceuticals, B.V.i.o.
Peng Bo
TraskBritt
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