Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.
Patent
1996-03-05
1999-02-23
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Scleroproteins, e.g., fibroin, elastin, silk, etc.
530402, 530408, 530410, 514 21, 522 68, 623 6, A61K 3817, A61F 216
Patent
active
058745378
ABSTRACT:
Collagen-based compositions as adhesives and sealants for medical use and preparation thereof are described. Prior to polymerization, soluble or partially fibrillar collagen monomers in solution are chemically modified with an acylating agent, sulfonating agent or a combination of the foregoing. The collagen compositions prepared accordingly can be used as medical adhesives for bonding soft tissues or be made in to a sealant film for a variety of medical uses such as wound closures and tendon wraps for preventing adhesion formation following surgery.
REFERENCES:
patent: 3438374 (1969-04-01), Falb et al.
patent: 3453222 (1969-07-01), Young
patent: 3515551 (1970-06-01), Audran et al.
patent: 4215200 (1980-07-01), Miyata et al.
patent: 4233360 (1980-11-01), Lucky et al.
patent: 4264155 (1981-04-01), Miyata
patent: 4264493 (1981-04-01), Battista
patent: 4349470 (1982-09-01), Battista
patent: 4388428 (1983-06-01), Kuzma et al.
patent: 4407787 (1983-10-01), Sternberger
patent: 4427808 (1984-01-01), Stol et al.
patent: 4451568 (1984-05-01), Schneider et al
patent: 4452925 (1984-06-01), Kuzma et al.
patent: 4453939 (1984-06-01), Zimmerman et al.
patent: 4488911 (1984-12-01), Luck et al.
patent: 4563490 (1986-01-01), Stol et al.
patent: 4565580 (1986-01-01), Miyata et al.
patent: 4581030 (1986-04-01), Bruns et al.
patent: 4606910 (1986-08-01), Sawyer
patent: 4650616 (1987-03-01), Wajs
patent: 4713446 (1987-12-01), DeVore et al.
patent: 4789663 (1988-12-01), Wallace et al.
patent: 4837285 (1989-06-01), Berg et al.
patent: 4839345 (1989-06-01), Doi et al.
patent: 4950699 (1990-08-01), Holman
patent: 4969912 (1990-11-01), Kelman et al.
patent: 5024742 (1991-06-01), Nesburn et al.
patent: 5067916 (1991-11-01), Kelman et al.
patent: 5104957 (1992-04-01), Kelman et al.
patent: 5112350 (1992-05-01), Civevchia et al.
patent: 5147514 (1992-09-01), Mechanic
patent: 5156613 (1992-10-01), Sawyer
patent: 5173295 (1992-12-01), Wehling
patent: 5190057 (1993-03-01), Sarfarazi
patent: 5209776 (1993-05-01), Bass et al.
patent: 5279825 (1994-01-01), Wehling
patent: 5290552 (1994-03-01), Sierra
patent: 5292362 (1994-03-01), Bass et al.
patent: 5294314 (1994-03-01), Nesburn et al.
patent: 5352715 (1994-10-01), Wallace et al.
patent: 5354336 (1994-10-01), Kelman et al.
patent: 5356614 (1994-10-01), Sharma
patent: 5412076 (1995-05-01), Gagnieu
patent: 5431790 (1995-07-01), Nesburn et al.
patent: 5441491 (1995-08-01), Verschoor et al.
Shimizu, et al., Biomat., Med. Dev. Art. Org., 5(1):49-66 (1977).
Shimizu, et al., Biomat., Med. Dev. Art. Org., 6(4):375-391 (1978).
Lloyd, et al., D.R., "biomedical and Dental Applications of Ploymers", C.G. Cobelein et al. (eds)., Plenum Press (1980), pp. 59-84.
"Collagen as a Biomaterial", Stenzel, et al., pp. 231-253 (1974).
"Polyurenthanes", Galligan, et al., J.D., Chapter 16, pp. 255-267 (1970).
"Bonding to Hard Dental Tissues", Buonocore, M.G., Chapter 15, pp. 225-254 (1970).
Surface Preparation and Various Adhesive Resins, Lee, Jr. et al., H.L., Chapter 17, pp. 269-289 (1970).
ARVO Annual Meeting Abstract Issue, Investigative Ophthalmology and Visual Science, De Toledo, et al., A.R., vol. 31 (1990), p. 317.
ARVO Annual Meeting Abstract Issue, Investigative Ophthalmology and Visual Science, De Toledo, et al., A.R., vol. 31 (1990), p. 387.
Kram, et al., H.b., Arch Surg, 119:1309-1311 (1984).
Scheele, et al., Surgery, 95(1):6-13 (1982).
Siedentop, et al., K.H., Laryngoscope, 93:1310-1313 (1983).
Epstein, et al., G.H., Annals of Otology, Rhinology & Laryngology, 95(1):40-45 (1986).
De Toledo, et al., ARVO Annual Meeting Abstract Issue, Investigative Opthalmalogy and Visual Science, 1556-14 (1990) Abstract.
Scott, et al., ARVO Annual Meeting Abstract Issue, Investigative Opthalmalogy and Visual Science, 431-11:30 (1990) Abstract.
Fisher, "Collagen Goes Beyond the Cosmetic", The New York Times, Jan. 29, 1991.
Science Watch,Fining a Natural Glue, The New York Times, 1990.
Braunwald, N., Evaluation of crosslinked gelatin as a tissue adhesive . . . , Surgery, 59:6:1024-1030, (1966).
Snyder, et al., "An improved 2, 4, 6-Trinitrobenzenesulfonic . . . ", Analytical Biochemistry, 64:284-288, (1975).
Aldrich Chemical Company Brochure, (1990).
DeVore Dale P.
Kelman Charles D.
C. R. Bard Inc.
Mohamed Abdel A.
Tsang Cecilia J.
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