Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Reexamination Certificate
2006-01-24
2006-01-24
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
C530S350000, C536S023200, C435S007100, C435S007800
Reexamination Certificate
active
06989244
ABSTRACT:
The present invention relates to methods of screening for compounds that inhibit signal transduction by inflammatory cytokines. The methods include providing a sample that contains a TAK1 and a TAB1; contacting the sample with a compound; detecting binding between the TAK1 and the TAB1; and selecting the compound if binding between the TAK1 and TAB1 is inhibited in the sample compared to a control.
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Matsumoto Kunihiro
Ohtomo Toshihiko
Sugamata Yasuhiro
Tsuchiya Masayuki
Chugai Seiyaku Kabushiki Kaisha
Fish & Richardson P.C.
Prouty Rebecca E.
Swope Sheridan
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