Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds hormone or other secreted growth regulatory factor,...
Patent
1998-04-28
2000-09-26
Bansal, Geetha P.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds hormone or other secreted growth regulatory factor,...
4241301, 4241321, 4241411, 4241431, 4241441, 4241521, 4241721, 5303871, 53038822, 53038823, 53038824, 53038885, 5303892, A61K 39395, C07K 1600, C12P 2108
Patent
active
061239410
ABSTRACT:
A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying .beta..sub.1 integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive.
Bissell Mina J.
Weaver Valerie M.
Aston David J.
Bansal Geetha P.
Mahoney John W.
Ross Pepi
The Regents of the University of California
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