Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Reexamination Certificate
2007-04-03
2009-08-11
Robinson, Hope A (Department: 1652)
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
C424S093700, C514S012200, C514S002600
Reexamination Certificate
active
07572440
ABSTRACT:
Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, trachea, interarticular menisci, intervertebral discs, ear, nose, ribs and other fibrocartilaginous tissues in a mammal.
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Cui, P. C. et al., “Repair of thyroid cartilage defect with bone morphogenetic protein,” Annals of Otology, Rhinology and Laryngology, 106(4), pp. 326-328 (1997).
Majstorovic, L. et al., “Biological repair of thyroid cartilage defects by osteogenic protein-1 (bone morphogenetic proteins-7) in dog,” Bone (Abstract), 24(4), p. 419, abstract No. 42 (1999).
Vukicevic, S. et al., “Thyroid and articular cartilage repair in dog and sheep by OP-1,” Bone (Abstracts), 24(4), p. 423, abstract No. 57 (1999).
Katic Vladimir
Sampath Kuber T.
Vukicevic Slobodan
Haley Jr. James F.
Mangasarian Karen
Robinson Hope A
Ropes & Gray LLP
Stryker Corporation
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