Method for rendering a substrate surface antithrombogenic and/or

Details Method for rendering a substrate surface antithrombogenic and/or Method for rendering a substrate surface antithrombogenic and/or

1990-08-06

1994-07-12

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424426, 424473, A61K 4730

Patent

active

053286987

ABSTRACT:
A shaped medical article of a polymeric substrate is extrusion coated with a composition which includes a bioactive agent dispersed in a matrix polymer. Preferred bioactive agents are temperature sensitive agents which undergo thermal decomposition at a temperature above the processing temperature of the matrix polymer. Preferred matrix polymers have a melting point of about 100.degree. C. or lower.

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