Method for remyelinating a demyelinized lesion due to injury...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S352000, C424S093700

Reexamination Certificate

active

07098027

ABSTRACT:
Demyelinated axons were remyelinated in the demyelinated rat model by collecting bone marrow cells from mouse bone marrow and transplanting the mononuclear cell fraction separated from these bone marrow cells.

REFERENCES:
patent: 5733542 (1998-03-01), Haynesworth et al.
patent: WO 99/43286 (1999-09-01), None
patent: WO 00/12683 (2000-03-01), None
patent: WO 03/038074 (2003-05-01), None
patent: WO 03/038075 (2003-05-01), None
patent: WO 03/038090 (2003-05-01), None
Deans, RJ, et al. 2000. Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 28: 875-884.
Szilvassy, SJ, et al. 2001. Differential homing and engraftment properties of hematopoietic progenitor cells from murine bone marrow, mobilized peripheral blood, and fetal liver. Blood 98: 2108-2115.
Noti, JD, et al. 2000. Structural and functional characterization of the leukocyte integrin gene CD11d. J. Biol. Chem. 275: 8959-8969.
Galy, A, et al. 1998. Hematopoietic progenitor cells of lymphocytes and dendritic cells. J. Immunotherapy 21: 132-141.
Watt, SM, et al. 2000. CD164—a novel sialomucin on CD34+ cells. Leuk. Lymph. 37: 1-25.
Oostendorp, Raj, et al. 1997. VLA-4-mediated interactions between normal human hematopoietic progenitors and stromal cells. Leuk. Lymph. 24: 423-435.
Quesenberry, PJ, et al. 1987. Stromal cell regulation of lymphoid and myeloid differentiation. Blood Cells 13: 137-146.
Lane, WJ, et al. 2000. Stromal-derived factor 1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. Blood 96: 4152-4159.
Supplementary material published online in conjunction with Pittenger et al., Science 284: 143-147. http://www.sciencemag.org/feature/data/983855.shl accessed Sep. 22, 2005. 7 pages.
Thomas CL, ed. 1997. Taber's Cyclopedic Medical Dictionary. F. A. Davis Co. pp. 257, 1168, and 1805.
d'Allemand G. 1995. in Laboratory Instrumentation, 4th ed., Haven MC et al., ed. Wiley and Sons, pp. 31-34.
Bianco P et al. 2000. Marrow stromal stem cells. J Clin Invest 105: 1663-1668.
Gessani S et al. 2000. in Macrophages, Paulnock DM, ed. Oxford University Press. pp. 45-50.
McCarthy DA, 2001. in Cytometric Analysis of Cell Phenotype and Function, McCarthy DA et al., eds. Cambridge University Press. pp. 20-24 and 222-224.
Patel D et al. 1998. in Cell Separation: A Practical Approach, Fisher et al., eds. Oxford University Press. pp. 71-73.
Yukinori Akiyama et al., “Transplantation of Clonal Neural Precursor Cells Derived from Adult Human Brain Establishes Functional Peripheral Myelin in the Rat Spinal Cord,”Experimental Neurology, 2001, pp. 27-39, vol. 167, © Academic Press, Inc.
D.R. Archer et al., “Myelination by Cryopreserved Xenografts and Allografts in the Myelin-Deficient Rat,”Experimental Neurology, 1994, pp. 268-277, vol. 125, © Academic Press, Inc.
Christopher R. R. Bjornson et al., “Turning Brain into Blood: A Hematopoietic Fate Adopted by Adult Neural Stem Cells in Vivo,”Science, Jan. 22, 1999, pp. 534-537, vol. 283.
W.F. Blakemore, “Remyelination of CNS axons by Schwann cells transplanted from the sciatic nerve,”Nature, Mar. 3, 1997, pp. 68-69, vol. 266.
W.F. Blakemore et al., “Extensive Oligodendrocyte Remyelination following Injection of Cultured Central Nervous System Cells into Demyelinating Lesions in Adult Central Nervous System,”Dev. Neurosci., 1988, pp. 1-11, vol. 10, © 1988 S. Karger AG, Basel.
R.M.E. Chalmers-Redman et al., “In VitroPropagation and Inducible Differentiation of Multipotential Progenitor Cells from Human Fetal Brain,”Neuroscience, 1997, pp. 1121-1128, vol. 76, No. 4, © 1996 IBRIO, Published by Elsevier Science Ltd, Great Britain.
Jonathan D. Flax et al., “Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes,”Nature Biotechnology, Nov. 1998, pp. 1033-1039, vol. 16.
R.J.M. Franklin et al., “Schwan Cell-Like Myelination Following Transplantation of an Olfactory Bulb-Ensheathing Cell Line Into Areas of Demyelination in the Adult CNS,”GLIA, 1996, pp. 217-224, vol. 17, © 1996 Wiley-Liss, Inc.
Fred H. Gage et al., “Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain,”Proc. Natl. Acad. Sci. USA, Dec. 1995, pp. 11879-11883, vol. 92.
M. Gumpel, “Transplantation of Human Embryonic Oligodendrocytes into Shiverer Brain,”Annals New York Academy of Sciences, 1987, pp. 71-85, vol. 495.
Osamu Honmou et al., “Restoration of Normal Conduction Properties in Demyelinated Spinal Cord Axons in the Adult Rat by Transplantation of Exogenous Schwann Cells,”The Journal of Neuroscience, May 15, 1996, pp. 3199-3208, vol. 16, No. 10, © 1996 Society for Neuroscience.
Toshio Imaizumi et al., “Transplanted Offactory Ensheathing Cells Remyelinate and Enhance Axonal Conduction in the Demyelinated Dorsal Columns of the Rat Spinal Cord,”The Journal of Neuroscience, Aug. 15, 1998, pp. 6176-6185, vol. 18, No. 16, ©1996 Society for Neuroscience.
Takaaki Kato et al., “Transplantation of Human Olfactory Ensheathing Cells Elicits Remyelination of Demyelinated Rat Spinal Cord,”GLIA, 2000, pp. 209-218, vol. 30, © 2000 Wiley-Liss, Inc.
Gene C. Kopen et al., “Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains,”Proc. Natl. Acad. Sci. USA, Sep. 1999, pp. 10711-10716, vol. 96.
Carlos Lois et al., “Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia,”Proc. Natl. Acad. Sci, USA, Mar. 1993, pp. 2074-2077, vol. 90.
Cindi M. Morshead et al., “Neural Stem Cells in the Adult Mammalian Forebrain: A relatively Quiescent Subpopulation of Subependymal Cells,”Neuron, Nov. 1994, pp. 1071-1082, vol. 13, © 1994, Cell Press.
M.P. Moyer et al., “Culture, Expansion, and Transplantation of Human Fetal Neural Progenitor Cells,”ransplantation Proceedings, 1997, pp. 1040-1041, vol. 29, © 1997 Elsevier Science Inc.
Brent A. Reynolds et al., “Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System,”Sciense, Mar. 27, 1992, pp. 1707-1710, vol. 255.
Clive N. Svendsen et al., “Long-Term Survival of Human Central Nervous System Progenitor Cells Transplanted into a Rat Model of Parkinson's Disease,”Experimental Neurology, 1997, pp. 135-146, vol. 148, © 1997 Academic Press.
David A. Utzachneider et al., “Transplantationof glial cells enhances action potential conduction of amyelinated spinal cord axons in the myelin-deficient rat,”proc. Natl. Acad. Sci. USA, Jan. 1994, pp. 53-57, vol. 91.
Booma D. Yandava et al., ““Global” cell replacement is feasible via neural stem cell transplantation: Evidence from the dysmyelinatedshrivermouse brain, ”Proc. Natl. Acad. Sci, USA, Jun. 1999, pp. 7029-7034.
Sasaki et al., “Transplantation Of An Acutely Isolated Bone Marrow Fraction Repairs Demyelinated Adult Rat Spinal Cord Axons,” GLIA, vol. 35, pp. 26-34 (2001).
Woodbury et al., “Adult Rat and Human Bone Marrow Stromal Cells Differentiate Into Neurons,” Journal of Neuroscience Research, vol. 61, pp. 364-370 (2000).
Azizi et al., “Engraftment And Migration of Human Bone Marrow Stromal Cells Implanted In The Brains of Albino Rats—Similarities To Astrocyte Grafts,” Proceedings of The National Academy of Science of USA, Medical Sciences, vol. 95, No. 7, Mar. 31, 1998, pp. 3908-3913.
Pittenger et al., “Multilineage Potential of Adult Human Mesenchymal Stem Cells,” Science, American Association For The Advancement of Science, vol. 284, No. 5411, Apr. 2, 1999, pp. 143-147.
Yin et al., “AC133, A Novel Marker For Human Hematopoietic Stem And Progenitor Cells,” Blood, vol. 90, No. 12, Dec. 15, 1

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for remyelinating a demyelinized lesion due to injury... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for remyelinating a demyelinized lesion due to injury..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for remyelinating a demyelinized lesion due to injury... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3650941

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.