Method for removing the transforming growth factor-β...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

Reexamination Certificate

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C530S412000, C530S350000, C424S198100

Reexamination Certificate

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06844427

ABSTRACT:
An adsorbent suitable for adsorption of a transforming growth factor-β (TGF-β) comprising a compound which has a log P value of at least 2.50 wherein P is a partition coefficient in an octanol-water system and which is immobilized on a water-insoluble carrier. TGF-β present in a body fluid can be efficiently removed by bringing the body fluid into contact with the adsorbent.

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Leo A., et al: “Partition Coefficients and Their Uses”Chemical Reviews,US, American Chemical Society, Washington, D.C., vol. 71, No. 6, Dec. 1, 1971.

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